Mapping metabolite change in the mouse brain after esketamine injection by ambient mass spectrometry imaging and metabolomics.

Front Psychiatry · 2023 · PMC10206402 · PMID 37234214

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an increasing trendno p-value reported

At the whole-brain level, we found esketamine mainly affects the glycerophospholipid metabolism pathways, especially PC and PE, corresponding with the previous research reports that animals with stress models show PC and PE have an increasing trend without significance ( 43 ).

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