Whole genome sequencing diagnostic yield for paediatric patients with suspected genetic disorders: systematic review, meta-analysis, and GRADE assessment.

Arch Public Health · 2023 · PMC10210272 · PMID 37231492

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a possible trendno p-value reported

The meta-regression output suggested a possible trend towards a greater diagnostic yield of the WGS technique compared to WES after controlling for relevant covariates, although not attaining statistical significance (adjusted OR: 1.13 [95% CI: 0.79 – 1.62], p = 0.5001).

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