Barely Significant
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MSCs' conditioned media cytokine and growth factor profiles and their impact on macrophage polarization.

Stem Cell Res Ther · 2023 · PMC10214600 · PMID 37231519

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might be significantno p-value reported
On the other hand, the contribution of other components of MSCs secretome (EVs or cytokines and growth factors beyond those analyzed in this study) might be significant enough to mitigate the difference between CM from 2D and 3D cultures when assessing their effect on macrophage polarization.

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