an increasing trendp < 0.01
In the case of RAB3A silencing, an overall mRNA decrease in all markers was observed in NG, as shown for synaptopodin (−3.93 FC, p < 0.01) and CD2AP (−2.18 FC, p < 0.05), whereas under glucose overload, an increasing trend was observed in all podocyte markers, significant for synaptopodin (3.15 FC, p < 0.01) and WT-1 (4.75 FC, p < 0.05) ( Figure 2 A).