Effect of Curcumin and Coenzyme Q10 Alone and in Combination on Learning and Memory in an Animal Model of Alzheimer's Disease.

Increase in transfer latency in SCO + CUR (100 mg/kg) (22.91 ± 1.29) and SCO + CoQ10 (200 mg/kg) (19.98 ± 2.96) was highly significant ( p < 0.001) and SCO + CUR (200 mg/kg) (17.8 ± 2.55) was less significant ( p < 0.050 when compared to SCO + Memantine group (14.40 ± 2.40), indicating relatively lesser improvement in memory in elevated plus maze ( Figure 2 ).

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