Study on the Mechanism for SIRT1 during the Process of Exercise Improving Depression.

Brain Sci · 2023 · PMC10216812 · PMID 37239191

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an increasing trendno p-value reported

An animal experiment demonstrated that rats under CUMS exhibited reductions in the expression of PGC-1α and FNDC5 in the skeletal muscle and BDNF in the hippocampus, whereas the three factors showed an increasing trend after exercise [ 53 ].

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