After multivariate analysis, a highly significant survival benefit was observed in favor of adjuvant RT, especially in patients who received R1/R2 resection [ 29 ].
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The Potential Role of Adjuvant Chemoradiotherapy in Patients with Microscopically Positive (R1) Surgical Margins after Resection of Cholangiocarcinoma.
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In the overall population of our study, we did not report statistically significant differences in RFS and OS between R1 patients treated with CHRT and CHT alone, but a positive trend in the CHRT subgroup was observed.