As we observed multiple significant genes located in 17q21.31, for this risk locus, we performed joint/conditional analysis, a process to identify which genes represent independent associations (i.e., jointly significant), and which genes are not significant after accounting for the predicted expression of other genes in the region (i.e., marginally significant).
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Mendelian Randomization and Transcriptome-Wide Association Analysis Identified Genes That Were Pleiotropically Associated with Intraocular Pressure.
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