MicroRNA-155-5p, Reduced by Curcumin-Re-Expressed Hypermethylated <i>BRCA1</i>, Is a Molecular Biomarker for Cancer Risk in <i>BRCA1</i>-methylation Carriers.

The results revealed an overall highly significant increase in the expression levels of miR-155-5p in patients compared to controls ( p = 0.0003) ( Figure 3 A).

also in 83,176 other papers

A comparison of the pairwise expression levels between miR-155-5p and mRNA BRCA1 within WBCs for each patient and carrier revealed a significant negative correlation ( p = 0.0001 and p = 0.034) ( Figure 7 A,B) for patients with breast and ovarian cancer, respectively, with marginal significance ( p = 0.055) for the carriers ( Figure 7 C), which was not the case for controls.

also in 3,088 other papers