Resveratrol Enhances Cytotoxic Effects of Cisplatin by Inducing Cell Cycle Arrest and Apoptosis in Ovarian Adenocarcinoma SKOV-3 Cells through Activating the p38 MAPK and Suppressing AKT.

Although RES or cisplatin alone did not generate a significant change in cyclin E1 expression, we observed a decreasing trend in protein expression when cisplatin-treated cells were incubated with RES at increasing concentrations, especially at 100 μM ( Figure 3 A,F). 2.4.

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