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3D-Printed Gastroretentive Tablets Loaded with Niclosamide Nanocrystals by the Melting Solidification Printing Process (MESO-PP).

Pharmaceutics · 2023 · PMC10220711 · PMID 37242629

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a decreasing trendno p-value reported
During the milling time of 6 h, it was observed that throughout the process, the particle size and PDI of the formulation followed a decreasing trend ( Table 1 ), finally obtaining suspended submicron particles of the drug with a particle size of 188.5 nm with a PDI of 0.186, confirming the obtaining of a monodisperse nanosuspension (NS).

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