Exploring the Role of Anionic Lipid Nanodomains in the Membrane Disruption and Protein Folding of Human Islet Amyloid Polypeptide Oligomers on Lipid Membrane Surfaces Using Multiscale Molecular Dynamics Simulations.

Regarding DLPC ( Figure 7 B,E), an overall trend of a decrease in bilayer thickness and a concomitant increase in APL in the presence of the protein was also found, except bilayer thickness in the PS-raft, where no significant change in bilayer thickness due to the protein was evident.

also in 1,523 other papers