Oral Administration of Human-Gut-Derived <i>Prevotella histicola</i> Improves Sleep Architecture in Rats.

histicola group, total sleep time gradually and significantly increased after bacteria administration ( p < 0.05); there was a 51.5 min increase on Day 7 of administration from the baseline and an increasing trend sustained until Day 3 of bacteria withdrawal (mean time increase: 63.2 min on Day 2).

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In strain-specific analyses, we observed increased sleep time with borderline significance, regardless of strain type, during P. histicola administration (data available on request).

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