Astragaloside IV ameliorate acute alcohol-induced liver injury in mice <i>via</i> modulating gut microbiota and regulating NLRP3/caspase-1 signaling pathway.

Ann Med · 2023 · PMC10228327 · PMID 37243569

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Compared with model group, the protein expression of NLRP3, Pro-caspase-1, IL-1β, and IL-18 in AS-IV-L, AS-IV-M, and AS-IV-H group significantly decreased ( p < 0.05), while there was a decreasing trend of the protein expression of Cleaved-Caspase-1 without statistical significance ( p > 0.05).

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