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Dendritic cell activation and cytokine response in vaccine breakthrough TBE patients after <i>in vitro</i> stimulation with TBEV.

Front Immunol · 2023 · PMC10228714 · PMID 37261350

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an observed trendno p-value reported
On the other hand, significantly higher levels of IL-6 in addition to an observed trend of higher expression of TNF-α measured after 6 days of in vitro stimulation of PBMC could support disruption of the blood–brain barrier and promote viral and immune cell influx into the CNS, leading to more severe disease in VBT TBE patients.

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