highly significantp < 0.001
All experiments were performed in triplicate, and paired t-test and one-way analysis of variance (ANOVA) were used to determine the significance of relative expression between groups, with p < 0.05 considered statistically significant, p < 0.01 considered highly significant, and p < 0.001 considered extremely significant. 3 Results 3.1 Determination of the main components of XXMD-C by UPLC/Q-TOF-MS The positive and negative ion modes of the total ion chromatogram (TIC) were obtained under the above-mentioned chromatographic and mass spectrometric conditions ( Figures 1A,B ).