Enhanced stability of the SARS CoV-2 spike glycoprotein following modification of an alanine cavity in the protein core.

PLoS Pathog · 2023 · PMC10231827 · PMID 37200378

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highly significantno p-value reported

Strong and highly significant correlations between RBD binding and authentic SARS CoV-2 neutralization (top panel) and to a lesser extent pseudoviral neutralization (bottom panel) were observed in keeping with the known important role that RBD-directed antibodies play in SARS CoV-2 neutralization.

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