Examining the relationship between the tumor size and TBR showed an increasing trend for [ 18 F]FOL ( Figure 2A , right) and a relatively constant TBR for [ 18 F]FDG ( Figure 2B , right).
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High folate receptor expression in gliomas can be detected <i>in vivo</i> using folate-based positron emission tomography with high tumor-to-brain uptake ratio divulging potential future targeting possibilities.
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