In silico evidence implicating novel mechanisms of Prunella vulgaris L. as a potential botanical drug against COVID-19-associated acute kidney injury.

Front Pharmacol · 2023 · PMC10232756 · PMID 37274117

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might be significantno p-value reported

As SARS-CoV-2 N protein can enhance TGF-β/Smad3 signaling to cause tubular epithelial cell death and AKI via the G1 cell cycle arrest mechanism, the regulation of TGFB1 might be significant in COVID-19 AKI ( Wang et al., 2022 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

In <i>silico</i> evidence implicating novel mechanisms of <i>Prunella vulgaris</i> L<i>.</i> as a potential botanical drug against COVID-19-associated acute kidney injury.

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