As a result of this aetiological complexity, genetic approaches to nsCLP have recently focused on genome‐wide association (GWA) studies which have identified ~50 nsCLP susceptibility loci, with several being highly significant in independent studies of diverse populations (Beaty et al., 2010 , 2013 ; Birnbaum et al., 2009 ; Huang et al., 2019 ; Leslie et al., 2016 , 2017 ; Ludwig et al., 2012 , 2017 ; Mangold et al., 2010 ; Sun et al., 2015 ; Welzenbach et al., 2021 ).
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