Single-cell atlas of the human neonatal small intestine affected by necrotizing enterocolitis.

Computational deconvolution of the bulk RNAseq samples revealed a nonsignificant trend towards an increase in the proportion of all macrophages (fold change = 7.7, q = 0.52, Figs 1E and S1C ), an increase in the inflammatory macrophages (fold change = 667, q = 0.02, Fig 2G ) and a decrease in the noninflammatory macrophages (fold change = 0.009, q = 0.02, Fig 2G ) and a nonsignificant decrease in the proportion of DCs in the NEC samples (fold change = 0.056, q = 0.29, Fig 2G , using FDR < 0.25 as measure of significance).

also in 5,406 other papers