Early serial circulating tumor DNA sequencing predicts the efficacy of chemohormonal therapy in patients with metastatic hormone-sensitive prostate cancer.

Transl Oncol · 2023 · PMC10236461 · PMID 37247504

Europe PMC DOI

hedged sentence

0.5300

closest p · 10.6× alpha

0.5300

boldest claim

The sentences

borderline significancep = 0.53not close (p > 0.1)

ctDNA status predicts the time to castration resistance The patients with initial detectable plasma ctDNA levels experienced a similar time to castration resistance as those with initial undetectable plasma ctDNA levels, with borderline significance (12.83 vs. 10.27 mo; p = 0.53; Fig. 3 F).

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