Metabolomic and transcriptomic analyses of Fmo5-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress response, unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism.

PLoS One · 2023 · PMC10237457 · PMID 37267233

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highly significantno p-value reported

Our results show highly significant differences between Fmo5 -/- and WT mice in both gene transcription and metabolite concentrations.

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