Rutin and Hesperidin Revoke the Hepatotoxicity Induced by Paclitaxel in Male Wistar Rats <i>via</i> Their Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities.

Evid Based Complement Alternat Med · 2023 · PMC10238143 · PMID 37275575

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Effects on Liver Oxidative Stress and Antioxidant Defense Parameters Paclitaxel was given intraperitoneally to rats for six weeks, resulting in a highly significant rise in liver LPO and a highly significant decrease in liver GSH content, as well as SOD and GPx activities.

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