highly significantp < 0.01
As expected, chi-square test showed that at all times of observation, the patients treated with the considered medications or hospitalized for the above-mentioned concomitant diseases were markedly more represented in MG and in non-MG population (highly significant, p < 0.01). 3.4 Patient costs The mean total annual costs per patient were €3771 for the first year, €2827 for the second and 2555 for the third year of follow-up, mainly driven by hospitalizations (€2198 for the first, €1316 for the second and €1054 for the third year) and drugs (€1,148, €1122 and €1122).