Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response.

Front Immunol · 2023 · PMC10239957 · PMID 37283743

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trending toward significanceno p-value reported

Under the stringent binding assay involving incubation in 1.5 M NaSCN, the avidity of the antibodies elicited by SAS- adjuvanted JRFL-L60-C3d trimers was higher and trending toward significance than that from SAS- adjuvanted JRFL trimer- vaccinated mice (G4 vs.

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