As shown in Figures 9A, B , PUE upregulated Nrf2 expression, ML385 significantly decreased Nrf2 expression, and there was a decreasing trend of HO-1 expression level with the decrease of NRF2 expression.
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Puerarin inhibited oxidative stress and alleviated cerebral ischemia-reperfusion injury through PI3K/Akt/Nrf2 signaling pathway.
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