The increase in the burden of p409–410-positive aggregates in cells transduced with CP fibrils showed a trend toward significance (Fig. 6f ).
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Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage.
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The increase in the burden of p409–410-positive aggregates in cells transduced with CP fibrils showed a trend toward significance (Fig. 6f ).