Beyond brain injury biomarkers: chemoattractants and circulating progenitor cells as biomarkers of endogenous rehabilitation effort in preterm neonates with encephalopathy.

Moreover, some observations were reported having only borderline significance when there was a meaningful rationale or when constant patterns were observed, because the scope of this pilot study was to highlight unknown pathophysiological pathways and correlations, that would be clarified by future studies, and not to come to final conclusions.

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On the contrary, there were reports of cases of severe asphyxia ( 79 ) or PVL where S100B levels presented an increasing trend over time ( 74 , 78 ).

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