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An integral perspective of canonical cigarette and e-cigarette-related cardiovascular toxicity based on the adverse outcome pathway framework.

J Adv Res · 2023 · PMC10248804 · PMID 35998874

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an increasing trendno p-value reported
It is also worth noting that the nicotine content of e-cigarettes is showing an increasing trend in recent years [281] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.