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Defective lysosomal acidification: a new prognostic marker and therapeutic target for neurodegenerative diseases.

Transl Neurodegener · 2023 · PMC10249214 · PMID 37287072

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an overall trendno p-value reported
While there are inconsistent results, there is an overall trend illustrating an increase of cathepsin levels in biofluids and tissues of AD and a decrease in PD.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.