highly significantP = 9.0 × 10 −7
In contrast, CSA knockout led to strong decrease of the EGFP expression in comparison to the parental cell line, which was highly significant for both cyclo-dA stereoisomers ( P = 9.0 × 10 −7 for 5′ R - and P = 8.5 × 10 −7 for 5′ S -cyclo-dA, heteroscedastic Student's t -test).