Standardization of Body Composition Status in Patients with Advanced Urothelial Tumors: The Role of a CT-Based AI-Powered Software for the Assessment of Sarcopenia and Patient Outcome Correlation.

After the first cycle of systemic therapy administration, the observed correlations remained stable and highly significant at both unilinear regression with the muscle-skeletal components (i.e., abdominal, psoas, and long spine muscle area [cm 2 /m 2 ]) reaching the highest degree of correlation with SMI-L3 also when adjusted with clinic confounders (r 2 : 0.874) ( Figure 2 A,B). 3.3.

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However, although not statistically significant, both SMI-L3 and its derived sarcopenia-related cut-off demonstrated an overlapping trend toward significance in line with the other individual aforementioned predictors (aOR: 0.96, 95% CI: 0.92–1.1 and aOR: 2.33, 95% CI: 0.99–5.52) ( Table S1A ).

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