Surprisingly, detectable T cell recognition of MAGEA12 in patient TILs did not correlate with high levels of auto-antibody, since we did not detect MAGEA12-specific T cells in 4 patients with highly significant anti-MAGEA12 auto-antibodies (Fig. 2 a, c).
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Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire.
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