highly significantP < 0.001
3A to D , the candidate recovered viruses, namely, rAdv-ChGM-CSF, rAdv-HN, and rAdv-ChGM-CSF-HN, had highly significant ( P < 0.001) mRNA gene expression differences in the HEK-293A-infected cells compared to the wtAdv-infected cells and nonchallenged [NC] noninfected cells.