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Monitoring medicine prescriptions before, during and after pregnancy in Italy.

PLoS One · 2023 · PMC10270638 · PMID 37319236

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an increasing trendno p-value reported
According to the therapeutic indication, gonadotropins showed the highest prescription level in the trimester immediately before the start of pregnancy, with an increasing trend with maternal age.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.