highly significantP<0.001
However, the temporal patterns of total epizootics ( Fig 2A ) and human cases ( Fig 2D ) (based on data from the Ministry of Health) and the YFV infection in NHP studied here were roughly equivalent ( Fig 2B ), and the temporal smooth was both highly significant (P<0.001; Table 2 ) and accounted for a large proportion of the model deviance (R = 0.54 and R = 0.22; Table 3 ).