ASIRs and ASMRs of primary liver cancer varied between regions, with an increasing trend in ASIR (EAPC = 0.91; 95% CI 0.47, 1.35) and a stable trend in ASMR (EAPC = 0.42, 95% CI − 0.01, 0.85) of primary liver cancer in high SDI region between 1990 and 2019.
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Global, Regional, and National Trends in Incidence and Mortality of Primary Liver Cancer and Its Underlying Etiologies from 1990 to 2019: Results from the Global Burden of Disease Study 2019.
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The ASIR of primary liver cancer was deemed to be in a decreasing trend in 89 countries or territories, with the largest decrease in Saint Kitts and Nevis (EAPC = − 4.70; 95% CI − 5.77, − 3.62) (Table S12 and Fig. 5 C).