Exploration of the impact of multimode thermal therapy versus radiofrequency ablation on CD8⁺ T effector cells of liver malignancies based on single cell transcriptomics.

Although the change in the ratio of immune cells was not signification in both groups, an increasing trend was observed in the proportions of T cells in the MTT group compared to the RFA group ( Figure 1E ).

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Then, the inter-group comparison was carried out on the 5 cell subsets, which revealed a significant increasing trend of CD8Teff_3 and a decreasing trend of CD8Teff_1 in the MTT group compared to the RFA group ( Figures 6B, C ).

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