Barely Significant
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Multi-strain probiotics alleviate loperamide-induced constipation by adjusting the microbiome, serotonin, and short-chain fatty acids in rats.

Front Microbiol · 2023 · PMC10272585 · PMID 37333632

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an increasing trendno p-value reported
Sert , Tph1 , and Tph2 , which are also related to serotonin, showed an increasing trend in the probiotic treatment groups, but a significant difference was not observed compared to the LOP group ( Supplementary Figure S2 ).

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