Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa.

iScience · 2023 · PMC10275975 · PMID 37332597

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These observations are highly significant in defining the role of c-MYC alone in creating highly differentiated epithelial cells of the crater filled with keratins, whereas Cyclin D1 and c-MYC caused hyperproliferation and dermal invasion of KA-type sSCCs ( Figures 8 B, 8C and S5 B).

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