Integrative single-cell sequencing analysis distinguishes survival-associated cells from the breast cancer microenvironment.

Interestingly, normal cells, tumor cells, and Scissor+ tumor cells showed an increasing trend of gradient in interactions with myeloid cells, T cells, and mesenchymal cells (Figure 6A–C ), implying that cancerous cells may need more interactions to domesticate surrounding cells for promoting their own exist, particularly Scissor+ tumor cells may have a stronger influence on cell communication (Figure S4A ).

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