Gut epithelial barrier dysfunction in lupus triggers a differential humoral response against gut commensals.

Front Immunol · 2023 · PMC10280985 · PMID 37346043

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highly significantno p-value reported

Furthermore, the highly significant correlation of IgM anti- B. acidifaciens antibody levels with IgM anti-dsDNA and the inhibition of binding of serum IgM to dsDNA by B. acidifaciens indicate that IgM antibodies produced in TLR7Tg mice might have a cross-reaction between bacterial and self-antigens.

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