Comparison of the therapeutic effects between stem cells and exosomes in primary ovarian insufficiency: as promising as cells but different persistency and dosage.

The serum AMH level was significantly decreased in POI mice (3.29 ± 0.08 ng/ml) and showed an increasing trend in MSC-treated mice (4.78 ± 2.19 ng/ml) but was not significant (Fig. 2 d).

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The serum E2 level showed a decreasing trend in POI mice (4.18 ± 0.79 pg/ml) that was reversed after MSC treatment (5.75 ± 2.00 pg/ml) but was not significant (Fig. 2 c).

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