A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.

Mol Neurodegener · 2023 · PMC10286470 · PMID 37349795

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highly significantno p-value reported

This idea is supported by the observation of the highly significant SNP × age interaction term for these loci, which for ULK2 , PTPRD , ADCY2 , and OSGIN1 were responsible for the significant joint effect to a much greater extent than the SNP’s main effect.

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