Simultaneous integrated dose reduction intensity-modulated radiotherapy effectively reduces cardiac toxicity in limited-stage small cell lung cancer.

Lower OAR parameters were also noted in the SDR-QD group treatment plans compared to the C-QD group; the statistical analysis ( Figure 4C and 4D ) showed the differences to be highly significant, with a P < 0.05 for the differences between the doses delivered to the heart and lungs.

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