This finding is in agreement with the results of the Lyon R90-01 trial, where, in the patients achieving pCR, a positive trend in survival was described, which is, however, influenced by disease recurrence at two years [ 24 ].
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pCR and 2-Year Disease-Free Survival: A Combination of the Two Endpoints as a New Classification for Locally Advanced Rectal Cancer Patients-An Updated Pooled Analysis of Eleven International Randomized Trials.
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