Proteomic Characterization of SAS Cell-Derived Extracellular Vesicles in Relation to Both BPA and Neutron Irradiation Doses.

Regarding changes in oxidation levels between the different irradiation conditions during BNCT, we did not detect a difference for Tyr, while for Met there was an increasing trend with higher irradiation (11.3 Gy) ( Figure S2 ), although with low statistically significant difference ( p -value = 0.15 and 0.09 comparing 0 Gy to 11.3 Gy conditions at 6 h and 24 h, respectively).

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Despite this preliminary evaluation showing an interesting trend in oxidation levels after BNCT, ad hoc experiments focused on redox proteomics and post-translational modifications research are required [ 42 ].

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