xProtCAS: A Toolkit for Extracting Conserved Accessible Surfaces from Protein Structures.

(C) SLIT and NTRK-like protein 5 ( O94991 ) structure with an equally conserved surface (on the top figure) leading to the top-ranked patch being barely significant ( p -value: 0.002) and ranks in the tail of the list of all human protein patches (rank: 27, 898).

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(A) Procollagen galactosyltransferase 1 ( Q8NBJ5 ) structure displaying conservation scores on the top figure (grey indicates low score, blue average score, and red high scores) and a highly significant top-ranked predicted patch on the bottom figure (the red color represent the defined patch, the grey color for the rest of the surface) ( p -value: 1.29 × 10 −18 ) making it ranks at the head of the list of all patches on human proteins (rank: 343).

also in 33,135 other papers