Non-Contrast and Contrast-Enhanced Cardiac Computed Tomography Imaging in the Diagnostic and Prognostic Evaluation of Coronary Artery Disease.

Finally, a meta-analysis of 70 studies comprising 41,534 subjects, mainly derived from community-based or hospital-based populations with low-to-intermediate pretest CAD probability, showed that EAT volume was independently associated with obstructive CAD (coronary stenosis and myocardial ischemia) and CAD events, whereas the correlation with CAC was only borderline significant [ 69 ].

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The same source reports a decreasing trend in morbidity and mortality from CAD, which has occurred despite a worsening in the risk profiles of Americans with atherosclerotic cardiovascular disease (ASCVD), [ 2 ] and is likely due to advances in the prediction, detection, and treatment of CAD.

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